Columbia University Medical Center
Ranked #1 in Psychiatry
U.S. News & World Report
Ranked #1 in Research Funding
National Institutes of Health
NewYork-Presbyterian Hospital The University Hospital of Columbia and Cornell

Ask the Experts


If someone has a first serious depressive episode, how likely is it that they will have another depressive episode in their life?

Answered by: Alexander Glassman

About half of individuals experiencing a major depression will only have a single episode in their whole life, but in the other half the episode will recur. Once it starts to recur, with each additional episode it becomes more likely to recur again.