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Ask the Experts


When in antidepressant treatment do sexual side effects occur?

Answered by: David Hellerstein

Sexual side effects due to antidepressants may emerge within a few days to a few months of starting medication depending upon a patient’s physiological makeup and response to the medication. Comparative studies report different time frames. Therefore, it is important to stay attuned of one’s sexual behavior pattern and note any changes in desire, arousal, or ability to orgasm. With heightened awareness, one can work with one’s psychiatrist to find the best treatment options.