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Question:

What are the most common sexual side effects of antidepressant (SSRI) medications?

Answered by: David Hellerstein

SSRIs (selective serotonin reuptake inhibitors) such as Prozac, Zoloft or Celexa are very effective in treating depression, but can cause sexual side effects.

The three most common antidepressant-induced sexual side effects include decreased sexual interest (libido), decreased physiological arousal (including lubrication in women and erection in men), and delayed or blocked orgasm.

Unusual and rare sexual side effects include priapism (or constant erection), clitoral priapism, painful ejaculation, penile anesthesia, increased libido and/or spontaneous orgasm with yawning.