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Ask the Experts


I was prescribed amitriptyline 10 mg for sleep. I took it approx 15 yrs ago and could not tolerate higher than 10mg. At 50mg I had tachycardia.

I am concerned that restarting it at this low dose that I may have cardiac side effects. Is that a real concern at 10mg? What are my other options?

Answered by: Philip Muskin

If you cannot tolerate this medication it makes sense to consider a consultation to review other options to address your difficulty with insomnia. If 10mg was not efficacious in the past, there is no reason to assume it will work now.