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Category: Lyme Treatment
What criteria do doctors use to choose different antibiotics?
Partly, doctors rely on what medicines have been shown in published
studies to be effective for Lyme Disease. For neurologic Lyme disease,
the best tested antibiotic is IV ceftriaxone ("Rocephin"). For early Lyme
Disease, the best tested antibiotics include oral doxycycline, cefuroxime
(ceftin) and amoxacillin. Physicians however often use other antibiotics
well. For example, because one mouse study and several in vitro studies
indicate that the agent of Lyme Disease can penetrate and lodge inside
cells, some doctors prefer to use medications that have good
intracellular penetration (such as clarithromycin (Biaxin)). Other factors
that go into the decision include whether the patient is allergic to a
particular family of antibiotics or whether the patient can tolerate oral
medications; intolerance might suggest the use of intramuscular
penicillin whereas if a person is allergic to penicillins or cephalosporins a
doctor would want to avoid long-acting intramuscular penicillin-family
medicines.
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