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Presbyterian Hospital
Room 4-124
622 West 168th St.
New York, NY   10032

Phone: 212-305-5020
Fax: 212-305-4981

-Columbia University
-College of Physicians & Surgeons
-Department of Medicine
-Division of Nephrology

Hospital Affiliations
New York-Presbyterian Hospital
The Allen Hospital

Open Training Positions
Undergraduate Students
Graduate Students

Tom Nickolas, MD, MS
Assistant Professor of Medicine at CUMC

Research Summary
Renal osteodystrophy
Kidney transplant related osteodystrophy
Fracture risk assessment and treatment in patients with kidney disorders
The epidemiology of kidney disease and its complications

Research Activities
Patients with chronic kidney disease have poor bone strength and increased fracture risk. Hip fractures, which tend to be debilitating, are particularly common and can result in an increased risk of death. My primary interest is the effect of kidney disease on the skeleton, with an emphasis on the microstructural and biochemical mechanisms by which kidney failure increases fracture risk. The identification of these mechanisms will lay the groundwork for the development and study of novel and effective fracture prevention strategies.

After kidney transplantation fracture risk is markedly increased, particularly at the spine and hip. We are currently studying risk factors for and the structural, microarchitectural and biochemical mechanisms of fracture after kidney transplantation. These data will advance the development of novel fracture prevention strategies for kidney transplant recipients.

Service Activities
Renal Osteodystrophy Clinic
Clinical evaluation of bone health and the implementation of state-of-the art techniques to assess and prevent fracture in patients with:
Chronic kidney diseases
End stage renal disease
Kidney transplantation

Positions & Appointments
2005-present Assistant Professor of Medicine Columbia University Medical Center New York, NY
2009-2012 Herbert Iriving Assistant Professor of Clinical Medicine Columbia University Medical Center New York, NY
2003-2005 Instructor of Clinical Medicine Columbia University Medical Center New York, NY

Education and Training
1989-1993 Biochemistry (BA) Rutgers College, New Brunswick, NJ
1993-1998 Medicine (MD) University of Pittsburgh School of Medicine, Pittsburgh, PA
1998-2000 Internal Medicine Internship The Hospital of the University of Pennsylvania, Philadelphia, PA
2000-2001 Internal Medicine Residency The Hospital of the University of Pennsylvania, Philadelphia, PA
2001-2003 Nephrology Fellowship New York Presbyterian Hosptial, Columbia University, New York, NY
2002-2004 Biostatistics (MS) The Mailman School of Public Health, Columbia University, New York, NY

Honors and Awards
1989 Phi Eta Sigma (National University Freshman Honor Society)
1992 Phi Beta Kappa (Attained the Junior level of undergraduate training)
1991 Henry Rutgers Scholar (Honors Program requiring the completion of an undergraduate Honors thesis)
1993 Summa cum laude in biochemistry
1997 Alpha Omega Alpha (National Medical School Honors Society)
1999 George Davey Howells Prize in Otolaryngology for Diseases of the Head & Neck, Nose and Throat
2002 Patient Oriented Research Scholarship, Columbia University
2006 International Society for Clinical Densitometry, Special Projects Award
2006 National Institutes of Health Loan Repayment Program
2006 Amgen Junior Faculty Research Award
2009 Herbert Irving Scholars Award, Columbia University

Committees and Society Memberships
Kidney Disease Improving Global Outcomes - Mineral and Bone Disease Consensus Group
National Institutes of Health: Kidney Research National Dialogue - Acute Kidney Injury Working Group

American Society of Nephrology (ASN)
International Society of Nephrology (ISN)
National Kidney Foundation (NKF)
American Society of Bone and Mineral Research (ASBMR)
The International Society of Clinical Densitometry (ISCD)

Special Interests
Novel bone imaging technologies
Fracture risk assessment in kidney diseases
Skeletal effects of post-transplantation immunosuppression
The impact of kidney disease and its complications in aging patients with chronic kidney disease

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