Richard Mayeux, M.D.
Gertrude H. Sergievsky Professor of Neurology, Psychiatry and Epidemiology (in the Gertrude H. Sergievsky Center and in the Taub Institute on Alzheimers Disease and the Aging Brain)
Director, Sergievsky Center,
Columbia University Medical Center
Co-Director, Taub Institute for Research on Alzheimer's Disease and the Aging Brain,
Columbia University Medical Center
Director, Memory Disorders Center,
New York State Psychiatric Institute
Dr. Mayeux is the Gertrude H. Sergievsky Professor of Neurology, Psychiatry and Epidemiology, and the Director of the Gertrude H. Sergievsky Center at Columbia University, a center devoted to the epidemiologic investigation of neurological diseases. He is also the Co-Director of The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain.
In 1992, he received the Leadership and Excellence in Alzheimer’s Disease award from the National Institute of Aging and in 2004 a MERIT award for his work on the genetic epidemiology of familial Alzheimer’s disease. Since 2002 he led the National Institute on Aging – Late Onset Alzheimer’s Disease family study.
Dr. Mayeux has been the author of over 300 papers, chapters and books dealing with various aspects of Alzheimer’s disease and other degenerative diseases of the aging brain. He has been the Robert Aird Visiting Professor at the University of California at San Francisco, the Emanuel Goldberg Visiting Professor at the University of Rochester and the J.L. Silversides Visiting Professor at the University of Toronto. He was the recipient of the Columbia University Dean’s Distinguished Clinical Scientist Award, and received the Rita Hayworth Award from the Alzheimer’s Association.
Dr. Mayeux is a Fellow of the American Academy of Neurology and the New York Academy of Science, a member of the American Neurological Association, and the Association of American Physicians. He is also a member of the Association for Research in Nervous and Mental Disease, Society for Epidemiologic Research and Society for Neuroscience. He has served as a member of the Aging Review and the Epidemiology of Chronic Disorders Committees for the National Institutes of Health and the Medical and Scientific Advisory Board for the Alzheimer’s Association. In 2000, he was elected to the Institute of Medicine of the National Academies, and in 2007 he was the recipient of the Potamkin Award for research on Alzheimer's disease and related disorders from the American Academy of Neurology.
Undergraduate: Oklahoma State University, B.S., 1968
Medical School: Oklahoma University School of Medicine, M.D., 1972
Internship: Boston City Hospital (Boston University), Medicine, 1972 - 1973
Residency: Boston City Hospital (Boston University), Medicine, 1973 - 1974
Residency: Columbia University (Neurological Institute of Columbia University Medical Center, Neurology, 1974 - 1977
Fellowship: Boston Veterans Administration Hospital (Aphasia Unit), Behavioral Neurology and Aphasia, 1977 - 1978
Post-Graduate: Mailman School of Public Health, M.S. Epidemiology, 1991
Board Certifications: Neurology and Psychiatry
Room 312 Unit/Box:P&S 16
622 West 168th St.
New York, NY 10032
I have led an epidemiological investigation of Alzheimer disease and related conditions known as the Washington Heights-Inwood Community Aging Project over a period of 18 years. We study the rates and risk factors for Alzheimer' disease among elderly from African-American and Caribbean Hispanic. I also directs a genetic study of Alzheimer's disease in Caribbean Hispanic families. We have completed two full genome-wide scans in these families and are working to fine map regions of interest. We recently identified genetic variants in the sortilin-related receptor, SORL1 related to Alzheimer's disease.
1. Honig L, Kukul B, Mayeux R: Atherosclerosis and AD: Analysis of data from the US national Alzheimer’s Coordinating Center.. Neurology 2005;64 : 494-500
1. Lee JH, Mayeux R , Mayo D, Santana V, Williamson J, Flaquer A, Ciappa A, Rondon HZ, Estevez P, Lantigua R, Kawari T, Toulina A, Medrano M, Torres M, Stern Y, Tycko R, Rogaeva E, St George-Hyslop, Knowles JA: Fine mapping of 10q and 18q for familial Alzheimer disease in Caribbean Hispanics. . Mol Psychiatry 2004;9: 1042-1051
1. Luchsinger JA, Tang M-X, Shea S, Mayeux R: Hyperinsulinemia and risk of Alzheimer’s disease. . Neurology 2004;63: 1187-1192
1. Mayeux R: Mapping the new frontier: complex genetic disorders.. Joural of Clinical Investigation 2005;115: 1404-1407
1. Tycko B, Lee JH, Ciappa A, Saxena A, Li C-M, Lin Feng L, Arriaga A, Stern Y, Lantigua R, Yang L, Shachter NS, Mayeux R: APOE and APOC1 promoter polymorphisms and Alzheimer’s disease in African-Americans and Caribbean Hispanics.. Archives of Neurology 2004;61: 1434-1439