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Joshua Gordon, MD, PhD
Associate Professor
Psychiatrist, Integrative Neuroscience,
New York State Psychiatric Institute
Assistant Attending,
New York Presbyterian Hospital
Dr. Gordon is a psychiatrist and neuroscientist who combines laboratory-based examining mouse models of human psychiatric illness with clinical practice and teaching in general psychiatry. He has received several awards and grants for his research, including NARSAD Young Investigator and IMHRO Rising Star Awards , as well as the A.E. Bennett Award from the Society for Biological Psychiatry. His work is funded by grants form the Hope for Depression Research Foundation, the International Mental Health Research Organization, and the National Institute of Mental Health.
Education and Training
Undergraduate: Washington University, A.B., 1985-1989
Medical School: University of California, M.D., 1989-1997
Doctoral Degree: University of California, Ph.D., 1989-1995
Residency: Columbia Univ Med Ctr - NYPH- NYSPI, Psychiatry Internship & Residency, 1997-2001
Fellowship: Columbia Univ Med Ctr - NYSPI, Research Fellowship, 2001-2004
Board Certifications: Psychiatry
Specialties
• Psychiatry
• Neuroscience
Contact information
Address:
NYS Psychiatric Institute
Room Kolb 136 Unit/Box:87
1051 Riverside Drive
New York, NY 10032
Phone: 212 543-6768
Fax: 212 543-1174
jg343@columbia.edu
Personal Homepage
research summary
Cloning of genes which predispose to neuropsychiatric illness is proceeding rapidly of late. Yet identifying such predisposition genes is but a first step in understanding the pathophysiology of mental illnesses. We study genetic models of these diseases from an integrative neuroscience perspective, focused on understanding how a given disease mutation leads to a behavioral phenotype in disease-related mouse models. To this end, we employ a range of systems neuroscience techniques, including in vivo anesthetized and awake behaving recordings.
Publications
1. T Sigurdsson, KL Stark, M Karayiorgou, JA Gogos, and JA Gordon: Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia.. Nature 2010;464: 763-767
2. A Adhikari, MA Topiwala, and JA Gordon: Single units in the medial prefrontal cortex with anxiety-related firing patterns are preferentially influenced by ventral hippocampal activity.. Neuron 2011;71: 898-910
3. Adhkari A Topiwala M Gordon JA: Sychronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety. Neuron 2010;65: 257-269
4. Gordon JA: Testing the glutamate hypothesis of schizophrenia. Nature Neuroscience 2010;13: 2-4
5. JA Gordon: Oscillations and hippocampal-prefrontal synchrony. Current Opinion in Neurobiology 2011;21: 584-491
