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John Chabot, MD, FACS

Positions and Appointments

2006-Present  Chief, Division of GI/Endocrine Surgery and Executive Director, Pancreas Center
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
2013-Present  Associate Director of Clinical Affairs, Herbert Irving Comprehensive Cancer Center
Columbia University, New York, NY
2011-Present  Vice President, ColumbiaDoctors
Columbia University College of Physicians and Surgeons, New York, NY
2009-Present  David V. Habif Professor of Clinical Surgery
Columbia University College of Physicians and Surgeons, New York, NY
1998-Present  Attending Surgeon
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY

Clinical Specialties

Surgical treatment of pancreatic, parathyroid, thyroid, and liver disease

Research Interests

Pancreatic cancer
Peritoneal mesothelioma


Education and Training

1983-1990  Internship/Residency/Fellowship, Transplantation
Columbia Presbyterian Medical Center, New York, NY
1983  MD
Dartmouth Medical School, Hanover, NH
1980-1982  Fellowship, Pathology
Mary Hitchcock Medical Center, Hanover, NH
1975-1979  BS, Engineering Science
Tufts University, Medford, MA

Board Certifications

American Board of Surgery, 1991

Professional Experience

1998-2008  Associate Professor of Clinical Surgery
Columbia University College of Physicians and Surgeons, New York, NY
2002-2006  Chief, Division of General Surgery
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1999-2004  Medical Director, Operating Rooms
Columbia University College of Physicians and Surgeons, New York, NY
1996-2002  Vice Chairman, Department of Surgery
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1995-2002  Chief, Hepatobiliary and Pancreatic Surgery
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1995-1997  Director, Surgical Intensive Care
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1992-1996  Associate Director, Surgical Residency Program
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1991-1998  Assistant Attending Surgeon
Columbia University College of Physicians and Surgeons, New York, NY
1991-1998  Assistant Professor of Surgery
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1991-1996  Surgical Chief, Thyroid Clinic
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY

Professional Honors

2008--Physician of the Year, Nursing Service of NewYork-Presbyterian Hospital
2004--Special Recognition Award,
NewYork--Presbyterian Hospital
1998--Thomas C. King Resident Teaching Award
1997--Teacher of the Year, P&S Graduating Class
1991--Habif Scholar
1990--Ortho Foundation Award
1990--Blakemore Award for Surgical Research
1987--88-Blakemore Prize for Surgical Research
1987--Upjohn Young Scientist Award
1985--1987-Irvington House Institute Fellowship
1979--Alpha Omega Alpha, Dartmouth Medical School
1979--Signa XI, Scientific Research Society
1978--Tau Beta Pi, National Engineering Honor Society
1978--Magna Cum Laude, Tufts University

Professional Societies and Committees

American Association of Endocrine Surgeons
American College of Surgeons, Fellow
American Hepato-Pancreato-Biliary Association
American Medical Association
New York Surgical Society
New York Transplantation Society


Current Projects


Government Grant: Principal Investigator, "Pancreatic Supplement for Cancer Center Grant" -

Selected Publications


Allendorf JD, Lauerman M, Bill A, DiGiorgi M, Goetz N, Vakiani E, Remotti H, Schrope B, Sherman W, Hall M, Fine RL, Chabot JA. Neoadjuvant chemotherapy and radiation for patients with locally unresectable pancreatic adenocarcinoma: feasibility, efficacy, and survival. Journal of Gastrointestinal Surgery. 2008 Jan;12(1):91-100. Epub 2007 Sep 5.

Fine Robert L, Fogelman David R, Schreibman Stephen M, Desai Manisha, Sherman William, Strauss James, Guba Susan, Andrade Riolan, Chabot John. The Gemcitabine, Docetaxel, and Capecitabine (GTX) Regimen for Metastatic Pancreatic Cancer: A Retrospective Analysis. Cancer Chemotherapy and Pharmacology (2008) 61:167-175.

Gumbs Andrew A, Bessler M, Milone L, Schrope B, Chabot J. The Contribution of Obesity to Pancreatic Carcinogenesis. Surgery for Obesity and Related Diseases, November 2007, accepted for publication.

Suciu-Foca N, Feirt N, Zhang QY, Vlad G, Liu Z, Lin H, Chang CC, Ho EK, Colovai AI, Kaufman H, D'Agati VD, Thaker HM, Remotti H, Galluzo S, Cinti P, Rabitti C, Allendorf J, Chabot J, Caricato M, Coppola R, Berloco P, Cortesini R. Soluble Ig-Like Transcript 3 Inhibits Tumor Allograft Rejection in Humanized SCID Mice and T Cell Responses in Cancer Patients. J Immunol. 2007 Jun 1;178(11):7432-41. PMID: 17513794.

Allendorf John D, Schrope Beth A, Inabnet William B, Chabot John A. Post-operative Glycemic Control in Patients Undergoing Central Pancreatectomy for Mid-Gland Lesions. World Journal of Surgery (2007) 31:164-8.

Fisher Jason C, Kuenzler Keith A, Bodenstein Lawrence, Chabot John A Central Pancreactectomy with Pancreaticogastrostomy in Children. Journal of Pediatric Surgery (2007) 42, 740-746.

Schonleben F, Qiu W, Bruckman KC, Ciau NT, Li X, Lauerman MH, Frucht H, Chabot JA, Allendorf JD, Remotti HE, Su GH. BRAF and KRAS Mutations in Intraductal Papillay Mucinous Neoplasm/Carcinoma (IPMN/IPMC) of the Pancreas. Cancer Letters Published online November 8, 2006.

Fogelman DR, Chen J, Chabot JA, Allendorf JD, Schrope BS, Ennis RD, Schreibman SM, Fine RL. The Evolution of Adjuvant and Neoadjuvant Chemotherapy and Radiation for Advanced Pancreatic Cancer: From 5-fluorouracil to GTX Surg Oncol Clin N. Am. 2004 Oct;13(4):711-35.

Frucht H, Stevens PD, Fogelman DR, Verna EC, Chen J, Chabot JA, Fine RL. Advances in the Genetic Screening, Work-up, and Treatment of Pancreatic Cancer. Curr Treat Options Gastroeneterol. 2004 Oct;7(5):343-354.

Goldstein MJ, Toman J, Chabot JA. Pancreaticogastrostomy: a novel application after central pancreatectomy J. Am College 2004 June;198(6):871-6

Joseph KA, El-Tamer M, Ditkoff BA, Chabot J, Komenaka I, Horowitz L, Schnabel F, Shutter J. Synchronous Presentation of Breast Cancer and Pheochromocytoma in a 57 Year Old Woman. Breast Journal 2004 Jan-Feb; 10(1):63-4

Allendorf John, Kim Lucy, Chabot John, DiGiorgi Mary, Spanknebel Kathryn, LoGerfo Paul. The Impact of Sestamibi Scanning on the Outcome of Para-thyroid Surgery. The Journal of Clinical Endocrinology & Metabolism 2003 Jul:88(7):3015-8 PMID:12843136 (PubMed – indexed for MEDLINE)

Taub Robert, Keohan Mary, Chabot John, et al. Peritoneal Mesothelioma Current Treatment Options in Oncology, Vol. 1, No. 4, Page 303-312 October 2000

Antman Karen, Mitchell C Benson, Chabot John, Cobrinik David, Grann Victor R, Jacobson Judith S, Joe Andrew K, Katz Aaron E, Kelly Kara, Neugut Alfred I, Russo Donna, Tiersten Amy, Weinstein I. Bernard. Complementary and Alterative Medicine: The Role of the Cancer Center Journal of Clinical Oncology, Vol 19, No 18s (September 15 Supplement, 2001:pp55s-60s

Horvath KD, Chabot JA. An Aggressive Resectional Approach to Cystic Neoplasms of the Pancreas. American Journal of Surgery 178(4):269-74, October 1999

Schwarz MA, Kandel J, Brett J, Li J, Hayward J, Schwarz RE, Chappey O, Wautier JL, Chabot JA, LoGerfo P, Stern D. Endothelial-monocyte Activating Polypeptide II, a Novel Antitumor Cytokine that Suppresses Primary and Metastatic Tumor Growth and Induces Apoptosis in Growing Endothelial Cells. Journal of Experimental Medicine 190(3):341-54, August 2, 1999

Mongero LB, Beck JR, Kroslowitz RM, Argenziano M, Chabot JA. Treatment of Primary Peritoneal Mesothelioma by Hyperthemic Intraperitoneal Chemotherapy. Perfusion 14(2):141-5, March 1999

Khan ZR, Neugut AI, Ahsan H, Chabot JA. Risk Factors for Biliary Tract Cancers. American Journal of Gastroenterology 94(1):149-52, January 1999

Marvin MR, Southhall JC, Trokhan S, DeRosa C, Chabot JA. Liver Metastases Are Enhanced in Homozygous Deletionally Mutant ICAM-1 or LFA-1 Mice. Journal of Surgical Research 80(2):143-8, December 1998

Marvin MR, Kayton ML, O’Toole KM, Rowe DH, DeRosa C, Kindred A, Trokhan S, Chabot JA, Kandel J. A Metastasizing Model of Anaplastic Human Wilms' Tumor in the Nude Mouse European Journal of Pediatric Surgery 8(5):295-8, October 1998

Hagopian EJ, Chabot JA, Oluwole SF, Benvenisty AI, Hardy MA. Allograft Rejection and Corticosteroids in Acute Pancreatitis Following Renal and Cardiac Transplantation. Transplantation Proceedings 29(1-2):583, Feb.-March 1997

Ditkoff BS, Chabot J, Feind CR, LoGerfo P. Parathyroid Surgery Using Monitored Anesthesia Care As An Alternative to General Anesthesia. American Journal of Surgery 172(6):698-703, Dec. 1996

Ditkoff BA, Marvin MR, Brichkow I, Yemul S, Chabot JA, Feind CR, LoGerfo P. The Detection of Circulating Thyroid cells in the Peripheral Bloodstream: Preoperative and Postoperative Analysis Thyroidology: Clinical and Experimental:8;87-94. 1996

Ditkoff BA, Marvin M, Yemul S, Shi Y. Chabot JA, Feind CR, LoGerfo P. Detection of Circulating Thyroid Cells in Peripheral Blood. Surgery 120(6):959-964, December 1996-Presented at the American Ass. of Endocrine Surgeons, Napa Valley, California, April 21-23, 1996.

Marvin MR, Libutti SK, Kayton M, Kao J, Hayward J, Grikscheit T, Yan Fan AB, Brett J, Weinberg A, Nowygrod R, LoGerfo P, Feind CR, Hansen KS, Schwarz M, Stern D, Chabot JA. A Novel Tumor-Derived Mediator That Sensitizes Cytokine-Resistant Tumors to Tumor Necrosis Factor. Journal of Surgical Research Vol. 63(1) 248-255, June 1996

Greenfeld JI, Chabot JA, Oluwole SF, Hardy MA. The Mechanism of UVB Prevention of Graft Versus Host Disease. J. Surg. Rec. 60(1):137-41, Jan.1996

Ditkoff BA, Chabot JA, LoGerfo P, Jin S, Feind CR. Hurthle Cell Cancer of the Thyroid: The Incidence of Multifocal and Bilateral Disease. Thyroidology: Clinical and Experimental,7(2) 49-54, January 1995

REVIEWS, CHAPTERS, AND EDITORIALS


Neugut A, Marvin MR, Pella, V. Chabot JA. An Overview of Adenocarcinoma of the Small Intestine Oncology (Huntington)11(4):529-550, April 1997

Chabot, JA. The Whipple Procedure – 1935 to 1993. P&S Review, 1993

Chabot JA, Altman RP. Thyroid and Parathyroid. Pediatric Surgery W. B. Saunders, 1993

King TC, Chabot JA, Geller PG. Surgery Pretest: Self-Assessment and Review. McGraw-Hill Inc. 1992

Perosa F, Hardy MA, Guarini L, Chabot JA, Dammacco F, Ferrone S. Anti-idiotypic monoclonal antibodies to anti-HLA class II monoclonal antibodies. Potential applications in the treatment of autoimmune diseases. In Recent Advances in Autoimmunity and Tumor Immunology ed Dammacco F, 1990

Hardy, MA, Chabot JA. Alteration of pancreatic islet immunogenicity using ultraviolet irradiation; synergism with peritransplant immunosuppression. In Transplantation of the Endocrine Pancreas eds. Van Schilfgaarde, R and Hardy MA. Elsevier Press VII:301-307, 1988

Reemtsma K, Chabot JA, Pi-Sunyer FX, Weber C. Isolation of zenogenic islets of langerhans for human transplantation; comparative studies of primate, human, Marine and rabbit islets. Proc. International Symposium on Artificial Organs, Biomedical Engineering and Transplantation. VCH Publishers, 1987

Hardy MA, Chabot JA, Tannenbaum G, Benvenisty AI. Graft acceptance; modification of immunogenisity of the donor or the donor organ with or without host immunosuppression. In Small Bowel Transplantation, Experimental and Clinical Fundamentals (Ed. Hammelman and Deltz) Springer-Verlag, 1987

Tannenbaum G, Benvenisty AI, Chabot JA, Hardy MA. Stoma or no stoma in intestinal transplantation. In Small Bowel Transplantation, Experimental and Clinical Fundamentals (Ed. Hammelman and Deltz) Springer-Verlag, 1987

Hardy MA, Chabot JA, Tannenbaum G, Lau HT. Immunomodulation by ultraviolet irradiation. Prog. Clin. Biol. Res. 224:119-138, 1986

ABSTRACTS


Stevens PD, Chabot JA, VandeMeirop F, Green PHR, Stein JA, Garcia-Carrasquillo RJ, Siegel LM, Diamond BD, Lightdale CJ. Endoscopic Retrograde Cholangiopancreatography Before or After Laparoscopic Cholecystectomy? A Randomized Trial. American Journal of Gastroenterology. In Press

Clinic pathologic Assessment in Patients with Peritoneal Malignant Mesothelioma: p16 Status and Mitotic Activity are Predictors of Survival Borczuk AC, Taub RN, Keohan ML, Hesdorffer M, Hibshoosh H. Chabot JA, Lee S, Alsberry R, Alexis D, Powell CA. Submitted 2004.

Biochemically Synergistic Chemotherapy for Advanced Pancreatic Cancer Fine Robert L., Sherman William, Chabot John, van Echo David, Cusnir Michael, Thomas Leno, Schreibman Stephen, Williams Michael, Richter Harold American Society of Clinical Oncology, Meeting 2002

Mortality, Morbidity and Cost-Related Outcomes in Acute Pancreatitis; A Prospective Study Finegold J, Stevens PD, Huynh J, Jenders RA, Diamond B, Poneros J, Slotweiner P, Chabot JA, Green PHR, Lightdale CJ. Gastroenterology 112:A15 1997

Implementation of a Standardized Multi-Disciplinary Treatment Protocol for Acute GI Hemorrhage Finegold J, Garcia-Carrasquillo RJ, Stevens PD, Van deMierop F, Green PHR, Battagliano M, Meyer F, Rosenberg R, Lewis SK, Rubin M, Chabot JA, Diamond B, Lightdale CJ. Gastrointestinal Endoscopy 43,356 1996

ERCP Before or After Laparoscopic Cholecystectomy? Final Results of Randomized Trial; Long Term Follow-up Van deMierop F, Stevens PD, Garcia-Carrasquillo RJ, Schmulewitz N, Green PHR, Stein JA, Chabot JA, Lightdale CJ. Gastroenterology 110,A480 1996

ERCP Before or After Laparoscopic Cholecystectomy? Final Results of a Randomized Trial; Analysis of Negative Outcomes Van deMierop F, Stevens PD, Green PHR, Chabot JA, Stein JA, Garcia-Carrasquillo RJ, Lightdale CJ. Gastroenterology 110,A479 1996

(Visit PubMed to view this faculty member's most recent articles.)






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