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Holly Moore, PH.D.
Assistant Professor of Neuroscience (in the Center for Neurobiology & Behavior and in Psychiatry
Assistant Professor of Neuroscience in Psychiatry,
Columbia University
Director ,Rodent Neurobehavioral Modeling Core ,
New York State Psychiatric Institute and Lieber Center for Schizohprenia Research, Columbia Univ
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Undergraduate: Wright State University, B.S., -1990
Graduate: Ohio State University, PhD, 1990-1995
Fellowship: University of Pittsburgh, PhD, 1995-1998
Post-Graduate: University of Pittsburgh, PhD, 1998-2002
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• Preclinical models of mood and psychotic disorders
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Phone: 212-543-6938
Fax: 212-543-1017
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| The Moore laboratory uses rodent and non-human primate preparations to model potential pathogenic mechanisms and treatment targets in schizophrenia and affective disorders. Specifically we focus on neurobehavioral systems, relating structural neuropathology to neural circuit function and, ultimately to behavior.
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1. Moore H, Jentsch JD, Ghajarnia M, Geyer MA, Grace AA: A neurobehavioral systems analysis of the effects of gestational exposure to methylazoxymethanol acetate (MAM) in the rat: implications for the neuropathology of schizophrenia.. Biolical Psychiatry 2006;60: 253-264
2. Meshi D, Drew MR, Ansorge MS, David, D, Saxe M, Santerelli L, Malapani C, Moore, H, Hen R.: Hippocampal neurogenesis is not required for the effect of environmental enrichment. Nature Neuroscience 2006;9: 729-731
3. Kellendonk C, Simpson EH, Polan HJ, Malleret G, Vronskaya S, Winiger V, Moore H, Kandel ER : Transient and selective over-expression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortical functioning. Neuron 2006;49: 603-615
4. Abi-Dargham A, Moore H : Prefrontal DA transmission at D1 receptors and the pathology of schizophrenia. The Neuroscientist 2003;9: 404-416
5. Lavin A, Moore H, Grace AA : Prenatal disruption of neocortical development alters prefrontal cortical neuron responses to dopamine in adult rats. Neuropsychopharmacology 2005;30: 1426-1435
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FACULTY ONLY
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