Eleanor Simpson, PhD
Asistant Professor of Clinical Neurobiology in Psychiatry

Research Scientist VI,
New York State Psychiatric Institute

 

 

Education and Training

Undergraduate:  University of Lancaster, BSc (hons)
Graduate:  University of Edinburgh, PhD
Fellowship:  HHMI/Columbia University

Specialties

Contact information

Address:
NYSPI Kolb Annex
Room 669  Unit/Box:87
1051 Riverside Drive
New York, NY   10032

Phone: 212-543-5243
Fax: 212-543-5474
es534@columbia.edu

research summary

Broadly, my research is focused on understanding the biological basis of behavior, in health and disease.

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Publications

1. Simpson EH, Kellendonk C, Ward RD, Richards V, Lipatova O, Fairhurst S, Kandel
ER, Balsam PD.: Pharmacologic rescue of motivational deficit in an animal model of
the negative symptoms of schizophrenia.  Biol Psychiatry  2011;69(10): 928-35

2. Ward RD, Simpson EH, Kandel ER, Balsam PD.: Modeling motivational deficits in mouse models of schizophrenia: behavior analysis as a guide for neuroscience.  Behav Processes  2011;87(1): 149-56

3. Simpson EH, Kellendonk C, Kandel ER.: A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia.  Neuron  2010;65(5): 585-96

4. Slifstein M, Kolachana B, Simpson EH, Tabares P, Cheng B, Duvall M, Frankle WG, Weinberger DR, Laruelle M, Abi-Dargham A.: COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C]NNC112 and PET.  Mol Psychiatry  2008;13(8): 821-7

5. Kellendonk C, Simpson EH, Polan HJ, Malleret G, Vronskaya S, Winiger V, Moore H, Kandel ER.: Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning.  Neuron  2006;49(4): 603-15