Denise Kandel, PH.D.
Professor of Sociomedical Sciences (in Psychiatry)
Professor, Dept. of Psychiatry,
Columbia University, College of Physicians & Surgeons
Professor, Dept. of Sociomedical Sciences,
Columbia University, Mailman School of Public Health
DENISE KANDEL, PH.D., Head of the Department of Epidemiology of Substance Abuse at the New York State Psychiatric Institute, Professor of Sociomedical Sciences and Psychiatry. Major interests: the epidemiology, risk factors, and consequences of drug use, in particular smoking; the epidemiology of substance dependence; developmental pathways of problem behaviors in adolescence; and the intergenerational transmission of deviance.
Current research activities focus on six areas: 1) the epidemiology of adolescent smoking; 2) the progression from experimentation to nicotine dependence; 3) the Gateway Hypothesis of drug involvement; 4) the intergenerational effects of parental drug use on child development and drug behavior; 5) comorbidity between substance use and psychiatric disorders; 6) animal models of epidemiological paradigms.
Undergraduate: Bryn Mawr College, B.A., 1950-1952
Graduate: Columbia University, M.A., 1952-1953
Doctoral Degree: Columbia University, Ph.D., 1953-1960
NYS Psychiatric Institute
1051 Riverside Drive
New York, NY 10032
1. Kandel DB: Stages and Pathways of Drug Involement: Examining the Gateway Hypotheis, Cambridge University Press, Cambridge, , England, 2002
2. Koob G, Kandel DB, Volkow ND: Psychiatric Pathophysiology: Addiction. Chapter 22 in Tasman A, Kay J, Lieberman J, First MB, Maj M (eds.) Psychiatry. Third Edition., John Wiley & Sons, West Sussex, , 2008
3. Hu M-C, Muthén B, Schaffran C, Griesler P, Kandel DB: Developmental Trajectories of Criteria of Nicotine Dependence in Adolescence. Drug Alc Depend 2008;98: 94-104
4. Griesler PC, Hu M_C, Schaffran, C, Kandel DB: Comorbidity of Psychiatric Disorders and Nicotine Dependence Among Adolescents: Findings from a Propective Longitudinal Study. J Am Acad of Child and Adolescent Psychiatry 2008;47: 1341-1351
5. Levine A, Huang YY, Drisaldi B, Griffin EA, Pollak DD, XU S, Yin D, Schaffran C, Kandel DB, Kandel ER: Molecular Mechanism for a Gateway Drug: Epigenetic Changes Initiated by Nicotine Prime Gene Expression by Cocaine. Sci Transl Med 2011;3 : 107ra109