Alan Brown, M.D., M.P.H.
Professor of Psychiatry and Epidemiology
Director, Program in Birth Cohort Studies ,
New York State Psychiatric Institute
Alan S. Brown, M.D., M.P.H. is Professor of Psychiatry and Epidemiology at Columbia University Medical Center, the New York State Psychiatric Institute and the Joseph L. Mailman School of Public Health. He is Director of the Program in Birth Cohort Studies at Columbia University Medical Center. Dr. Brown earned his undergraduate degree at Johns Hopkins University and received his medical degree from Jefferson Medical College. He completed his residency training in psychiatry at the University of Pittsburgh, followed by a postdoctoral fellowship in schizophrenia research at Columbia, and received his M.P.H. degree in epidemiology from Columbia’s Mailman School of Public Health.
Dr. Brown’s main area of research is on the identification of early antecedents for schizophrenia, bipolar disorder, and autism. Among his major findings, he was the first to demonstrate that serologically documented prenatal exposure to influenza, rubella, toxoplasmosis, and inflammatory biomarkers are potential risk factors for schizophrenia.
He leads 2 NIH-funded research grants aimed at identifying risk factors for schizophrenia and autism in a large national Finnish birth cohort, in collaboration with Turku University and THL in Finland. He also leads a large birth cohort study on the antecedents of bipolar disorder in northern California. Additionally, Dr. Brown leads a Conte Center Project on prenatal SSRIs and neuropsychiatric outcomes in Finland. He is on the core faculty of several research fellowships and has mentored over 30 trainees.
He is the recipient of several awards in clinical psychiatric research, including the A.E. Bennett Research Award. He has received numerous research grants as PI from the NIMH, NIEHS, NARSAD, and other funding agencies. He is a fellow of the American College of Neuropsychopharmacology and the WPA Section on Epidemiology.
Dr. Brown is an author or co-author of over 140 peer-reviewed publications, reviews, and book chapters.
Undergraduate: Johns Hopkins University, B.A., 1983
Graduate: Mailman School of Public Health, M.P.H., 2007
Medical School: Jefferson Medical College, M.D., 1987
Internship: Montefiore Hospital, Medicine/Psychiatry, 1987 - 1988
Residency: Western Psychiatric Institute and Clinic, General Psychiatry, 1988 - 1991
Fellowship: Columbia University, Schizophrenia Research, 1991-1994
Board Certifications: American Board of Psychiatry and Neurology
• Schizophrenia and other psychotic disorders
• Bipolar Disorder
NYSPI Kolb Annex
Room 125 Unit/Box:23
1051 Riverside Drive
New York, NY 10032
I am interested in improving our understanding of the relationship between early developmental insults and risk of schizophrenia, bipolar disorder, and autism, as well as the effects of these insults on brain structure and function.
1. Canetta SE, Bao Y, Co MD, Ennis FA, Cruz J, Terajima M, Shen L, Kellendonk C, Schaefer CA, Brown AS.: Serological documentation of maternal influenza exposure and bipolar disorder in adult offspring.. American Journal of Psychiatry 2014;171: 557-563
2. Canetta S, Sourander A, Surcel HM, Hinkka-Yli-Salomäki S, Leiviskä J, Kellendonk C, McKeague IW, Brown AS.: Elevated maternal C-reactive protein and increased risk of schizophrenia in a national birth cohort.. American Journal of Psychiatry 2014;171: 960-968
3. Gyllenberg D, Sourander A, Surcel HM, Hinkka-Yli-Salomäki S, McKeague IW, Brown AS.: Hypothyroxinemia during gestation and offspring schizophrenia in a national birth cohort.. Biological Psychiatry 2015;in press
4. Brown AS, Sourander A, Hinkka-Yli-Salomäki S, McKeague IW, Sundvall J, Surcel HM.: Elevated maternal C-reactive protein and autism in a national birth cohort.. Molecular Psychiatry 2014;19: 259-264
5. Malm H, Sourander A, Gissler M, Gyllenberg D, Hinkka-Yli-Salomäki S, McKeague IW, Artama M, Brown AS.: Pregnancy complications following prenatal exposure to SSRIs or maternal psychiatric disorder. Results from a Population-based national register data.. American Journal of Psychiatry 2015;in press