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Emmanuelle Passegue
Director
Alumni Professor


Address: 701 168th Street Hammer Health Sciences Room 726A New York NY 10032
Phone: 212-305-2433
Fax:
E-mail:

ep2828@cumc.columbia.edu

Education and Training:
Molecular Biology 1986-1990, Paris-XI University
Molecular and Cellular Endocrinology 1990-1995, Paris-XI University
Postdoctoral Fellow 1996-2000, Institute of Molecular Pathology
Postdoctoral Fellow 2001-2003, Stanford University
Research Associate 2003-2005, Stanford University
Affiliations:
Training Activities:
Research Summary:
(800 words, max)
Current Research:
I am widely recognized for my expertise on hematopoietic stem cell (HSC) biology. My research over the past 10-years has focused on understanding the cellular and molecular processes controlling HSC activity during homeostasis, and addressing how these regulations are changed in myeloid malignancies and physiological aging. My goal is to identify affected genes and/or pathways that can be use to develop new therapies to treat human diseases. Towards this end, my laboratory are employing a variety of cross-disciplinary approaches using mouse models and human patient samples. Current projects investigate the role of apoptosis, autophagy, immune regulations, DNA repair mechanisms, and changes in the bone marrow (BM) niche microenvironment in HSC function in normal, stress, leukemic and aging conditions.
Publications:
(6 max)
URL for lab page:
 

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